Anterior polar cataract: clinical spectrum and genetic linkage in a single family.
作者： Alexander Ionides , Vanita Berry , Donna MacKay , Alan Shiels , Shomi Bhattacharya
DOI: 10.1038/EYE.1998.53
关键词: Surgery 、 Lens (anatomy) 、 Anterior polar cataract 、 Eye disease 、 Chromosome 17 (human) 、 Single family 、 Genetic linkage 、 Medicine 、 Visual acuity 、 Ophthalmology 、 Minimal effect
摘要: Anterior polar cataract can occur as a sporadic finding, in association with other ocular abnormalities or an inherited, autosomal dominant disorder. We have demonstrated linkage family anterior to the short arm of chromosome 17, locating gene region 17p12-13. All affected members this large had opacity at pole lens that varied only size and effect on visual acuity. is thought minimal acuity although there was high incidence unilateral amblyopia.
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