The Acute Effects of Fine Particulate Matter Constituents on Blood Inflammation and Coagulation

摘要: Limited evidence is available on the effects of various fine particulate matter (PM2.5) constituents blood inflammation and coagulation. We examined associations between 10 circulating biomarkers in a panel 28 urban residents with four repeated measurements Shanghai, China. Based linear mixed-effect models, we fitted single-constituent constituent-PM2.5 joint constituent-residual models to evaluate PM2.5 eight inflammatory (fibrinogen, C-reactive protein, monocyte chemoattractant protein-1, tumor necrosis factor-α, interleukin-1b, intercellular adhesion molecule-1, P-selectin, vascular cell molecule-1) two coagulation (plasminogen activator inhibitor-1 soluble CD40 ligand). found robust organic carbon (OC), elemental (EC), nitrate (NO3–), ammonium (NH4+) at least 1 8 markers. On average, an interquartile ...