Glycans from streptococcal cell walls. Immunological and chemical properties of a new diheteroglycan from Streptococcus faecalis.

作者: John H. Pazur , John S. Anderson , Walter W. Karakawa

DOI: 10.1016/S0021-9258(18)62378-6

关键词: Cell wallDisaccharideMicrobiologyBiologyAntigenRhamnoseStreptococcusMoietyBiochemistryGlycanGalactose

摘要: Abstract The cell wall of Streptococcus faecalis, strain N, has been found to contain two antigenic glycans, a diheteroglycan glucose and galactose tetraheteroglycan rhamnose, glucose, galactose, N-acetylgalactosamine. present report describes the isolation, purification, structural immunochemical characterization hitherto unknown diheteroglycan. A tentative structure proposed for new glycan on basis information oligosaccharides isolated from acid hydrolysates polymer immunological inhibition studies. Of considerable interest is finding that, major disaccharide moieties (lactosyl gentiobiosyl) in glycan, lactosyl moiety immunodominant group.

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