The choline-converting pathway in Staphylococcus xylosus C2A: genetic and physiological characterization.
作者： Ralf Rosenstein , Detlinde Futter-Bryniok , Friedrich Götz
DOI: 10.1128/JB.181.7.2273-2278.1999
关键词: Choline dehydrogenase 、 Membrane transport protein 、 Gene 、 Choline 、 Staphylococcus xylosus 、 Biology 、 Betaine-aldehyde dehydrogenase 、 Choline transport 、 Gene cluster 、 Biochemistry 、 Molecular biology
摘要: A Staphylococcus xylosus C2A gene cluster, which encodes enzymes in the pathway for choline uptake and dehydrogenation (cud), to form osmoprotectant glycine betaine, was identified. The cud locus comprises four genes, three of encode proteins with significant similarities those known be involved transport conversion other organisms. physiological role products confirmed by analysis deletion mutants. fourth possibly codes a regulator protein. Part cluster shown transcriptionally regulated elevated NaCl concentrations as inducers.
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