Effect of Anti-Müllerian hormone (AMH) and bone morphogenetic protein 15 (BMP-15) on steroidogenesis in primary-cultured human luteinizing granulosa cells through Smad5 signalling

作者: Ermioni Prapa , Anna Vasilaki , Konstantinos Dafopoulos , Eleni Katsiani , Panagiotis Georgoulias

DOI: 10.1007/S10815-015-0494-2

关键词: Follicle-stimulating hormoneProgesterone metabolismMouse OvarySignallingInternal medicineSignal transductionBiologyAnti-Müllerian hormoneBone morphogenetic protein 15In vitro fertilisationEndocrinology

摘要: … FSH activity is related to an increase in StAR mRNA [52] and protein … AMH had no effect on basal StAR-IR, FSH significantly increased StAR protein expression while BMP-15 and AMH …

参考文章(57)
Ioannis E. Messinis, Christina I. Messini, Konstantinos Dafopoulos, The role of gonadotropins in the follicular phase Annals of the New York Academy of Sciences. ,vol. 1205, pp. 5- 11 ,(2010) , 10.1111/J.1749-6632.2010.05660.X
N. Josso, C. Pieau, R.L. Cate, S. Ghaffari, B. Vigier, N. di Clemente, R.B. Pepinsky, A quantitative and interspecific test for biological activity of anti-müllerian hormone: the fetal ovary aromatase assay. Development. ,vol. 114, pp. 721- 727 ,(1992) , 10.1242/DEV.114.3.721
M. Karamouti, P. Kollia, A. Kallitsaris, N. Vamvakopoulos, G. Kollios, I. E. Messinis, Modulating effect of leptin on basal and follicle stimulating hormone stimulated steroidogenesis in cultured human lutein granulosa cells. Journal of Endocrinological Investigation. ,vol. 32, pp. 415- 419 ,(2009) , 10.1007/BF03346478
Fumio Otsuka, Kirsten J. McTavish, Shunichi Shimasaki, Integral role of GDF-9 and BMP-15 in ovarian function Molecular Reproduction and Development. ,vol. 78, pp. 9- 21 ,(2011) , 10.1002/MRD.21265
M. Breckwoldt, N. Selvaraj, D. Aharoni, A. Barash, I. Segal, V. Insler, A. Amsterdam, Cell proliferation and apoptosis Expression of Ad4-BP/cytochrome P450 side chain cleavage enzyme and induction of cell death in long-term cultures of human granulosa cells Molecular Human Reproduction. ,vol. 2, pp. 391- 400 ,(1996) , 10.1093/MOLEHR/2.6.391
Jennifer L. Dube, Pei Wang, Julia Elvin, Karen M. Lyons, Anthony J. Celeste, Martin M. Matzuk, The Bone Morphogenetic Protein 15 Gene Is X-Linked and Expressed in Oocytes Molecular Endocrinology. ,vol. 12, pp. 1809- 1817 ,(1998) , 10.1210/MEND.12.12.0206
Laura Pellatt, Suman Rice, Nafi Dilaver, Amira Heshri, Raymond Galea, Mark Brincat, Kristy Brown, Evan R. Simpson, Helen D. Mason, Anti-Müllerian hormone reduces follicle sensitivity to follicle-stimulating hormone in human granulosa cells. Fertility and Sterility. ,vol. 96, pp. 1246- 1251 ,(2011) , 10.1016/J.FERTNSTERT.2011.08.015
Elisa Di Pasquale, Paolo Beck-Peccoz, Luca Persani, Hypergonadotropic ovarian failure associated with an inherited mutation of human bone morphogenetic protein-15 (BMP15) gene. American Journal of Human Genetics. ,vol. 75, pp. 106- 111 ,(2004) , 10.1086/422103
Minna M Pulkki, David G Mottershead, Arja H Pasternack, Pranuthi Muggalla, Helen Ludlow, Maarten van Dinther, Samu Myllymaa, Katri Koli, Peter ten Dijke, Mika Laitinen, Olli Ritvos, None, A covalently dimerized recombinant human bone morphogenetic protein-15 variant identifies bone morphogenetic protein receptor type 1B as a key cell surface receptor on ovarian granulosa cells. Endocrinology. ,vol. 153, pp. 1509- 1518 ,(2012) , 10.1210/EN.2010-1390
Annemarie de Vet, Joop S.E. Laven, Frank H. de Jong, Axel P.N. Themmen, Bart C.J.M. Fauser, Antimüllerian hormone serum levels: a putative marker for ovarian aging. Fertility and Sterility. ,vol. 77, pp. 357- 362 ,(2002) , 10.1016/S0015-0282(01)02993-4