作者: Gabriela B. Gomez , Geoffrey P. Garnett , Helen Ward
DOI: 10.1097/OLQ.0B013E31818B2116
关键词: Population 、 Observational study 、 Meta-regression 、 Sexually transmitted disease 、 Antibiotic misuse 、 Pediatrics 、 Multivariate analysis 、 Meta-analysis 、 Random effects model 、 Medicine 、 Demography
摘要: Background: Estimated prevalence of self-medication for sexually transmitted diseases (STDs) in observational studies differs between and it may vary according to population characteristics. Methods: We investigated the extent use STD explored study level factors correlated variability observed populations. Medical databases were systematically searched published studies. Crude data extracted. Pooled estimates calculated using random effects models. Univariate multivariate meta-regression models with categorical covariates constructed. Results: Of 35 that met inclusion criteria all use, 20 also included analysis antibiotic only use. There was significant heterogeneity present across self-medication, Q = 3954.82, P <0.001; among 3797.94, <0.001. In analyses, publication year seemed explain 22.5% variation only. No other associations or characteristics found. Conclusions: leading high levels identified. Publications before 2000 seem a higher self-medication. Greater risk awareness misuse improved control availability at might this result. An individual should indicate which are influential whether their local can better.