The axonemal ultrastructure of spermatozoa from men with asthenospermia
作者： Andrew D. Hancock , David M. de Kretser
DOI: 10.1016/S0015-0282(16)54917-6
关键词: Semen 、 Sperm motility 、 Motility 、 Axoneme 、 Sperm 、 Semen analysis 、 Biology 、 Male infertility 、 Radial spoke 、 Andrology
摘要: Objective To determine with the use of transmission electron microscopy (TEM) proportion patients semen pattern severe asthenospermia ( Design Transverse sections sperm tail axonemes were quantitatively analyzed, and mean frequency per axoneme doublet microtubules, central pair, outer dynein arms, inner radial spokes determined. Setting Patients being investigated for male infertility at Reproductive Medicine Clinic Monash Medical Centre (Melbourne). Semen samples processed analyzed by TEM in university laboratory. Ten asthenospermic whom repeated analysis demonstrated a percentage motility Main Outcome Measure(s) The main measure was quantitative axonemes. hypothesis that reduction axonemal components causes lowered derived from results. Results Individual significant reductions least three structures when compared normal mean. Statistical grouped data showed all significantly lower than Conclusions consistent strongly suggests deficiencies are cause patients.
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sci-hub.se 参考文章(10)
Leeanda J. Wilton, Peter D. Temple-Smith, H.W. Gordon Baker, David M. de Kretser, Human male infertility caused by degeneration and death of sperm in the epididymis Fertility and Sterility. ,vol. 49, pp. 1052- 1058 ,(1988) , 10.1016/S0015-0282(16)59960-9
C. A. Yates, Caroline Thomas, G. T. Kovacs, D. M. de Kretser, Andrology, Male Factor Infertility and IVF Springer, London. pp. 95- 111 ,(1989) , 10.1007/978-1-4471-1664-6_8
ERIK BLOM, A New Sterilizing and Hereditary Defect (the ‘Dag Defect’) located in the Bull Sperm Tail Nature. ,vol. 209, pp. 739- 740 ,(1966) , 10.1038/209739A0
A. ROSS, S. CHRISTIE, M. G. KERR, An electron microscope study of a tail abnormality in spermatozoa from a subfertile man. Reproduction. ,vol. 24, pp. 99- 103 ,(1971) , 10.1530/JRF.0.0240099
L J Wilton, H Teichtahl, P D Temple-Smith, D M de Kretser, Structural heterogeneity of the axonemes of respiratory cilia and sperm flagella in normal men. Journal of Clinical Investigation. ,vol. 75, pp. 825- 831 ,(1985) , 10.1172/JCI111778
B. Bartoov, F. Eltes, J. Langsam, M. Snyder, J. Fisher, Ultrastructural studies in Morphological assessment of human spermatozoa International Journal of Andrology. ,vol. 5, pp. 81- 96 ,(1982) , 10.1111/J.1365-2605.1982.TB00306.X
H. PEDERSEN, Absence of Arms in the Axoneme of Immobile Human Spermatozoa Biology of Reproduction. ,vol. 12, pp. 541- 544 ,(1975) , 10.1095/BIOLREPROD12.5.541
Robert Dale McClure, James Brawer, Bernard Robaire, Ultrastructure of immotile spermatozoa in an infertile male: a spectrum of structural defects**Supported by the Medical Research Council of Canada, and the Fraser Memorial Fund of the Royal Victoria Hospital. Fertility and Sterility. ,vol. 40, pp. 395- 399 ,(1983) , 10.1016/S0015-0282(16)47309-7
Rune Eliasson, Björn Mossberg, Per Camner, Björn A. Afzelius, The immotile-cilia syndrome. A congenital ciliary abnormality as an etiologic factor in chronic airway infections and male sterility. The New England Journal of Medicine. ,vol. 297, pp. 1- 6 ,(1977) , 10.1056/NEJM197707072970101
Roger A. Williamson, James K. Koehler, W. Dianne Smith, Morton A. Stenchever, Ultrastructural sperm tail defects associated with sperm immotility Fertility and Sterility. ,vol. 41, pp. 103- 107 ,(1984) , 10.1016/S0015-0282(16)47549-7