A randomized phase II study of biweekly irinotecan monotherapy or a combination of irinotecan plus 5-fluorouracil/leucovorin (mFOLFIRI) in patients with metastatic gastric adenocarcinoma refractory to or progressive after first-line chemotherapy

作者: Sun Jin Sym , Junshik Hong , Jinny Park , Eun Kyung Cho , Jae Hoon Lee

DOI: 10.1007/S00280-012-2027-3

关键词: Stomach cancerFluorouracilOncologyGastroenterologyRefractoryPhases of clinical researchInternal medicineChemotherapyRandomized controlled trialMedicineConfidence intervalIrinotecan

摘要: … In this trial, 40 metastatic or locally advanced gastro-oesophageal junction or gastric … a reasonable second-line chemotherapeutic backbone for patients with advanced gastric cancer. …

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