The effect of acute exercise on undercarboxylated osteocalcin in obese men

摘要: The purpose of this study was to examine if the reduction in glucose post-exercise is mediated by undercarboxylated osteocalcin (unOC). Obese men were randomly assigned do aerobic or power exercises. change unOC levels correlated with post-exercise. post-acute exercise may be partly related increased unOC. Osteocalcin (OC) its (unOC) form contribute regulation homeostasis. As reduces serum and improves insulin sensitivity obese individuals type 2 diabetes (T2DM), we hypothesised that benefit Twenty-eight middle-aged (52.4 ± 1.2 years, mean ± SEM), (BMI = 32.1 ± 0.9 kg m−2) either 45 min (cycling at 75% VO2peak) (leg press one repetition maximum plus jumping sequence) Blood samples taken baseline up 2 h At baseline, negatively (r = −0.53, p = 0.003) glycosylated haemoglobin (HbA1c) (r = −0.37, p = 0.035). Both exercises reduced (from 7.4 ± 1.2 5.1 ± 0.5 mmol L−1, p = 0.01 8.5 ± 1.2 6.0 ± 0.6 mmol L−1, p = 0.01, respectively). Aerobic significantly OC, high-molecular-weight adiponectin, while had a limited effect on OC Overall, those higher HbA1c greater reductions after (r = −0.46, p = 0.013 r = −0.43, p = 0.019, In sub-group people T2DM, percentage (r = −0.51, p = 0.038). This reports (especially exercise)