Advanced hydrogels for treatment of diabetes.

摘要: Diabetes mellitus is a chronic disease characterized by high levels of glucose in the blood, which leads to metabolic disorders with severe consequences. Today, there no cure for diabetes. The current management diabetes and derived medical conditions, such as hyperglycemia, cardiovascular diseases or diabetic foot ulcer, includes life style changes hypoglycemia based therapy, do not fully restore euglycemia functionality damaged tissues patients. This encourages scientists work outside their boundaries develop routes that can potentially tackle disorders. In this regard, acellular cellular approaches have represented an alternative diabetics, although treatments still face shortcomings related limited effectiveness immunogenicity. advent biomaterials has brought significant improvements approaches, three-dimensional extracellular matrix analogous, hydrogels, played key role regard. Advanced hydrogels are being developed monitor blood release insulin, well serve therapeutic technology. Herein, state art advanced improving treatment diabetes, from laboratory technology commercial products approved drug safety regulatory authorities, will be concisely summarized discussed. [Abstract copyright: article protected copyright. All rights reserved.]