Contrast Induced Acute Kidney Injury and its Impact on Mid-Term Kidney Function, Cardiovascular Events and Mortality.

摘要: The existence and clinical relevance of contrast induced acute kidney injury (CI-AKI) is still heavily debated angiographic procedures are often withheld in fear CI-AKI, especially CKD-patients. We investigated the incidence CI-AKI cardiovascular high risk patients undergoing intra-arterial angiography its impact on mid-term function, events mortality. conducted a prospective observational trial planned procedures. All subjects received standardized intravenous hydration prior to application. was defined according ≥25% increase creatinine from baseline either 24hrs or 48hrs after angiography. Plasma eGFR were recorded institutional medical record system one three months hospital discharge. Patients followed up for two years investigate long term effects studied 706 (317 female) with mean 52.0 ± 15 ml·min−1·1.73 m−2. 10.2% (72 patients). In 94 (13.3%) serum decreased 24 48 hours had lower higher at baseline, but no other independent predictors could be identified. Kidney function not different between both groups After year follow overall 56.5% group 58.8% Non (p = 0.8), myocardial infarctions, however, CI-AKI-patients. Overall survival also (88.6%) without (84.7%, p = 0.48). occurrence did have any negative Considerable fluctuations interfere presumed diagnosis CI-AKI. Necessary should