A Comparison of Drug Conditioning and Craving for Alcohol and Cocaine

摘要: Craving is a potentially important concept that difficult to define and study in the laboratory. Although alcohol cocaine are very different pharmacologically, this discussion emphasizes common factors addiction these drugs, such as tendency of alcoholics abusers crave substances. I review commonalities drug conditioning cue reactivity cocaine. Both drugs support Pavlovian when they presented unconditioned stimuli, whether studied rodents or humans. In addition, both craved with stimuli associated drugs. Finally, propose theoretical definition craving based on autoshaping sign-tracking phenomena suggests mechanism This model defines reflection sign tracking internal external have past reliably predicted presentation