8.12 Reduction of C X to CH 2
作者： J.W. Burton
DOI: 10.1016/B978-0-08-097742-3.00814-4
关键词: Chemistry 、 Aldehyde 、 Methyl group 、 Clemmensen reduction 、 Ionic bonding 、 Ketone 、 Deoxygenation 、 Organic chemistry 、 Hydrogenolysis 、 Methylene
摘要: The complete reduction of the carbonyl group an aldehyde or ketone to a methylene/methyl is generally achieved using well-known Wolff–Kishner and Clemmensen reductions these two transformations form majority chapter. A range useful procedures along with possible side reactions presented; examples will be mainly taken from recent literature. use ionic hydrogenation metal-catalyzed hydrogenolysis, predominantly aromatic ketones aldehydes, also presented. Other methods are briefly discussed.
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