First 5 years of measles elimination in southern Africa: 1996–2000

摘要: Summary Background Measles is the leading cause of vaccine-preventable death in Africa. Regional measles elimination considered feasible using current vaccines and a series WHO-recommended strategies. We aimed to interrupt transmission measles, use case-based surveillance show effect such interruption. Methods In southern Africa from 1996, seven countries with total population approximately 70 million relatively high routine vaccination coverage implemented addition immunisation at 9 months age, these included nationwide catch-up campaigns among children aged 14 years, then follow-up every 3–4 years 9–59 months, establishment serological diagnostic confirmation. Results Nearly 24 were vaccinated, overall 91%. Reported clinical cases declined 60 000 1996 117 laboratory-confirmed 2000. deaths 166 zero No increase adverse events was noted after campaign. Conclusion A reduction mortality morbidity can be achieved very low-income countries, that split their by geographical area or age-group target population, where initial infants