Evidence of Resistance to Tumour Grafts in the Offspring of Immunized Rats

摘要: For many years various experiments have been devised in order to find out whether an acquired characteristic can be inherited, but the results on whole do not appear received general scientific sanction. C. P. Martin and Bradford Hill recent both made surveys of this subject, from different points view. (1937), making a survey literature difficulties which confront experimentalist indicates possible causes for apparent discrepancies results. He also raises existence temporary form inheritance obeys Mendelian laws. (1934) reviews great deal work has done possibility resistance bacterial infection being inherited. that much is unconvincing, as it very difficult case infections quite sure offspring experimental animals infected some extent, well parents. The recorded paper resulted observations course our propagation Jensen’s rat sarcoma. This tumour easily transplanted one another by subcutaneous inoculation small grafts, when sensitive breed used rarely retrogresses, provided scrupulous technique followed (Chambers Scott 1930). Many ago we noticed rats tumours had disappeared were so susceptible grafts other same breed, seemed worth while how far apparently was transmitted offspring. data now provide evidence support view extent.