Positron emission tomography with computed tomography imaging (PET/CT) for the radiotherapy planning definition of the biological target volume: PART 1

作者: Pierpaolo Alongi , Riccardo Laudicella , Isacco Desideri , Agostino Chiaravalloti , Paolo Borghetti

DOI: 10.1016/J.CRITREVONC.2019.01.011

关键词: Biological targetMedicinePositron emission tomographyPET-CTComputed tomographyRadiologyVolume (compression)Radiation therapyMolecular imagingFunctional imaging

摘要: Abstract Aim Functional and molecular imaging, including positron emission tomography with computed imaging (PET/CT) is increasing for radiotherapy (RT) definition of the target volume. This expert review summarizes existing data functional modalities RT management, in terms volume delineation, following anatomical districts: brain (for primary secondary tumors), head/neck lung. Materials methods A collection available published was made, by PubMed a search. Only original articles were carefully critically revised. Results For tumors, amino acid PET radiotracers could be useful to identify microscopic residual areas differ between recurrence treatment-related alterations case re-irradiation. As head neck neoplasms may benefit from precise PET/CT-based due major capability high-risk areas. In lung cancer, PET/CT both delimit tumor collapsed lungs as predictive parameter treatment response. Conclusion Taken together, approaches offer step individualize radiotherapeutic care going forward. Nevertheless, several uncertainties remain on standard method properly assess information tumors.

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