SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination
作者： Waaqo Daddacha , Allyson E. Koyen , Amanda J. Bastien , PamelaSara E. Head , Vishal R. Dhere
DOI: 10.1016/J.CELREP.2017.08.008
关键词: Cell biology 、 DNA repair 、 Genome integrity 、 SAMHD1 、 Homologous recombination 、 DNA 、 Cancer 、 Molecular biology 、 Biology 、 Mutant 、 Resection
摘要: DNA double-strand break (DSB) repair by homologous recombination (HR) is initiated by CtIP/MRN-mediated DNA end resection to maintain genome integrity. SAMHD1 is a dNTP …
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