Time and Dose Dependent Antipyretic Investigations of Ethanolic Leaves and Fruits Extracts of Prosopis cineraria L. (Druce)
作者： Mahmood Ahmad , Haji Muhammad Shoaib Khan , Kamran Bashir , Imran Shair Mohammad , Muhammad Wajid
DOI:
关键词: Fruit extracts 、 Glycoside 、 Surgery 、 Dose dependence 、 Body weight 、 Prosopis cineraria 、 Traditional medicine 、 Antipyretic 、 Medicine 、 Phytochemical 、 Rectal temperature
摘要: The aim of this Study was to establish a comparative investigation Antipyretic activity ethanolic extract leaves and fruits the Prosopis cineraria phytochemical evaluation extracts these parts. Crude plant at dose 200 300 mg/kg body weight were used evaluate antipyretic activity. These evaluated by inducing brewer’s-yeast induced pyrexia in albino rats. Results presented as Mean ± SEM using SPSS 12.0. Leaves fruit decreases hyperpyrexia significant level when results compared standard control. shows effects lowering rectal temperature rats than 200mg/kg while both reduce significantly. that parts contain saponins, tannins, pholobatannins, flavanoids, alkaloids, steroids cardiac glycosides. indicate possess different doses which establishes scientific basis for its traditional uses i.e. rheumatism. Keywords: , Pyrexia, Paracetamol, brewer’s-yeast,
iiste.org参考文章(22)
Venugopalan Rajesh, Chellappan David Raj, Ramasamy Vijaya Muthu Manikandar, Perumal Perumal, Ramanathan Sambath Kumar, Analgesic and anti -pyretic activity of stem bark of Prosopis cineraria (Linn) Druce. Journal of Pharmacy Research. ,vol. 2, pp. 660- 662 ,(2009)
Bercy Uzcátegui, Dinorah Ávila, Heberto Suárez-Roca, Luis Quintero, José Ortega, Beatriz González, None, Anti-inflammatory, antinociceptive, and antipyretic effects of Lantana trifolia Linnaeus in experimental animals. Investigacion Clinica. ,vol. 45, pp. 317- 322 ,(2004)
Shuxin Li, Wenkai Dou, Ying Tang, Sarita Goorha, Leslie R. Ballou, Clark M. Blatteis, Acetaminophen: antipyretic or hypothermic in mice? In either case, PGHS-1b (COX-3) is irrelevant. Prostaglandins & Other Lipid Mediators. ,vol. 85, pp. 89- 99 ,(2008) , 10.1016/J.PROSTAGLANDINS.2007.10.007
Qaiser Jabeen, Samra Bashir, Badiaa Lyoussi, Anwar H. Gilani, Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities. Journal of Ethnopharmacology. ,vol. 122, pp. 123- 130 ,(2009) , 10.1016/J.JEP.2008.12.016
A. Ahmadiani, M. Javan, S. Semnanian, E. Barat, M. Kamalinejad, Anti-inflammatory and antipyretic effects of Trigonella foenum-graecum leaves extract in the rat. Journal of Ethnopharmacology. ,vol. 75, pp. 283- 286 ,(2001) , 10.1016/S0378-8741(01)00187-8
Tayfun Berkan, Levent Üstünes, Ferzan Lermioglu, Asli Özer, Antiinflammatory, analgesic, and antipyretic effects of an aqueous extract of Erythraea centaurium. Planta Medica. ,vol. 57, pp. 34- 37 ,(1991) , 10.1055/S-2006-960011
RN Almeida, DS Navarro, JM Barbosa-Filho, Plants with central analgesic activity. Phytomedicine. ,vol. 8, pp. 310- 322 ,(2001) , 10.1078/0944-7113-00050
Wamtinga Richard Saw ., Rainatou Boly ., Marius Lompo ., Noya Some ., Charles Euloge Lamie ., Innocent Pierre Guis ., Odile Germaine Nacou ., Anti-inflammatory, Analgesic and Antipyretic Activities of Dicliptera verticillata International Journal of Pharmacology. ,vol. 2, pp. 435- 438 ,(2006) , 10.3923/IJP.2006.435.438
Esra Küpeli, Müberra Koşar, Erdem Yeşilada, K.Hüsnü C Başer, A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species. Life Sciences. ,vol. 72, pp. 645- 657 ,(2002) , 10.1016/S0024-3205(02)02200-2
JA Sunilson, P Jayaraj, R Varatharajan, J Thomas, J James, M Muthappan, Analgesic and Antipyretic Effects of Sansevieria Trifasciata Leaves African Journal of Traditional, Complementary and Alternative Medicines. ,vol. 6, pp. 529- 533 ,(2010) , 10.4314/AJTCAM.V6I4.57191