CURRENT CONTROVERSIES AND FUTURE DIRECTIONS IN BASAL GANGLIA RESEARCH : Integrating Basic Neuroscience and Clinical Investigation

作者: Norberto Garcia-Cairasco , Euripedes C. Miguel , Scott L. Rauch , James F. Leckman

DOI: 10.1016/S0193-953X(05)70354-3

关键词: Neurologic diseaseBehavioral analysisBasal gangliaNeuroscienceResearch strategiesClinical investigationFunctional anatomyCognitionPsychologyStructural organization

摘要: A number of contemporary neurobiologic, neuropsychiatric, neurologic, and neurosurgical aspects basal ganglia research are reviewed in this issue. Remarkable progress is evident nearly every area endeavor. In concluding article, the authors have selected four areas for discussion, which touch on a range promising strategies, highlight few present controversies field. The article begins with discussion promise behavioral analysis across mammalian species as means studying functional anatomy ganglia, its role learning memory, well other forms cognitive processing. Second, considered some competing views how structural organization circuitry relate to performance routines. Third, genetic developmental perspectives function considered. closing, return relevance these complex neurobehavioral systems, understanding treatment psychiatric neurologic disease.

参考文章(102)
Thomas R. Insel, James T. Winslow, Neurobiology of obsessive compulsive disorder. Psychiatric Clinics of North America. ,vol. 15, pp. 813- 824 ,(1992) , 10.1016/S0193-953X(18)30211-9
I. Kermadi, J. P. Joseph, Activity in the caudate nucleus of monkey during spatial sequencing Journal of Neurophysiology. ,vol. 74, pp. 911- 933 ,(1995) , 10.1152/JN.1995.74.3.911
James F. Leckman, Donald J. Cohen, R. Arlen Price, Mark A. Riddle, Ruud B. Minderaa, George M. Anderson, David L. Pauls, The Pathogenesis of Tourette Syndrome Springer, Boston, MA. pp. 257- 272 ,(1986) , 10.1007/978-1-4684-5038-5_14
Transcranial magnetic stimulation: a neuropsychiatric tool for the 21st century. Journal of Neuropsychiatry and Clinical Neurosciences. ,vol. 8, pp. 373- 382 ,(1996) , 10.1176/JNP.8.4.373
David J. Kupfer, Floyd E. Bloom, Psychopharmacology: The Fourth Generation of Progress ,(1995)
Thomas Götz, Udo Kraushaar, Jörg Geiger, Joachim Lübke, Thomas Berger, Peter Jonas, Functional Properties of AMPA and NMDA Receptors Expressed in Identified Types of Basal Ganglia Neurons The Journal of Neuroscience. ,vol. 17, pp. 204- 215 ,(1997) , 10.1523/JNEUROSCI.17-01-00204.1997
F Eblen, AM Graybiel, Highly restricted origin of prefrontal cortical inputs to striosomes in the macaque monkey The Journal of Neuroscience. ,vol. 15, pp. 5999- 6013 ,(1995) , 10.1523/JNEUROSCI.15-09-05999.1995