Studies on catecholamines, renin and aldosterone following Catapresan (2-(2,6-dichlor-phenylamine)-2-imidazoline hydrochloride) in hypertensive patients.
作者： Bernt Hökfelt , Hans Hedeland , John-Fredrik Dymling
DOI: 10.1016/0014-2999(70)90212-8
关键词: Renin–angiotensin system 、 Endocrinology 、 Sympathetic nervous system 、 Urinary system 、 Aldosterone 、 Internal medicine 、 Bradycardia 、 Pharmacology 、 Blood pressure 、 Medicine 、 Hydrochloride 、 Plasma renin activity
摘要: Abstract The effect of the antihypertensive compound 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride (St 155, Catapresan®) on urinary catecholamines, plasma renin activity and aldosterone was studied in patients with hypertensive diseases different types. Catapresan induced marked lowering blood pressure bradycardia all cases except phaeochromocytoma. fall closely related to a reduction aldosterone. These findings are interest relation catapresan also respect possible role sympathetic nervous system for regulation production Our studies indicate that reduced decreased catecholamines is at least one mode action catapresan. It seems importance diminished which occurs following
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