Reliability of corneal thickness and endothelial cell density measures.
作者： Mark A Bullimore , Jason J Nichols , Gregory M Kosunick
DOI: 10.3928/1081-597X-20030501-12
关键词: Endothelial cell density 、 Intraclass correlation 、 Cornea 、 Optics 、 Corneal pachymetry 、 Materials science 、 Ophthalmology 、 Limits of agreement 、 Ultrasound 、 Reliability (statistics) 、 Pachymeters
摘要: PURPOSE: We evaluated the reliability and agreement between Orbscan, an ultrasonic pachymeter (Humphrey 855), Konan SP 9000-LC in terms of central corneal thickness. The was also used to study endothelial cell density measures. METHODS: Twenty-five normal subjects were examined on two occasions (mean separation = 9 ± 5 days) by a single examiner using all three instruments for pachymetry. Center Method manual counting method performed examiners determine density. Reliability assessed calculating 95% limits (LoA) intraclass correlation coefficients (ICC). RESULTS: For pachymetry test-retest reliability, -20 +17 µm ultrasound, -27 +22 Konan, -13 +13 Orbscan. There fair-to-good pachymeters (intraclass range 0.85 0.92). -498 +530, -482 +333 cells/mm 2 1 2, respectively. overlaid grid -355 +355, -535 +670 CONCLUSIONS: Orbscan good, although estimating fair, at best. [J Refract Surg 2003;19:344-352]
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