Clinical Diagnostics and Patient Stratification for Use in the Dental Office

作者: Alexandra B. Plonka , William V. Giannobile

DOI: 10.1007/978-3-319-23297-3_5

关键词: Patient stratificationPrognosticsHealth careDentistryBiomarker (cell)Intensive care medicinePersonalized medicineSalivary diagnosticsPeriodontal diseaseDiseaseMedicine

摘要: Diagnostics and prognostics in dentistry can be applied to stratify patients according risk for individualized disease forecasting and, ultimately, targeting resources maximize health outcomes. Traditional clinical measures of periodontal show a history tissue destruction but are unable determine biologic onset or initiation inflammation fail predict susceptibility progression disease. The state the art diagnostics is point-of-care (POC) methods (use microbial, protein biomarker, genetic measures). POC may use lab-on-a-chip (LOC) devices analyze oral fluids such as saliva. This technology patient stratification predictive modeling optimize personalized care dental office target healthcare those at highest risk.

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