Direct C–O Bond Activation Mediated by AcOH: A New Metal-Free Way for α-Functionalization of Ferrocene Alcohols
作者： Ran Jiang , Xue-Qiang Chu , Xiao-Ping Xu , Bin Wu , Shun-Jun Ji
DOI: 10.1071/CH11167
关键词: Biocatalysis 、 Acetic acid 、 Catalysis 、 Chemistry 、 Organic chemistry 、 Supramolecular chemistry 、 Reaction mechanism 、 Green chemistry 、 Methylene 、 Combinatorial chemistry 、 Ferrocene
摘要: α-functionalization of ferrocenyl alcohols by direct C–O bond activation indoles, active methylene compounds, electron-rich arenes, anilines, alcohols, and thiols in acetic acid is described. This protocol provides a relatively green efficient combinatorial access to ferrocene derivatives metal-free manner.
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