作者: T.L. Gilchrist
DOI: 10.1016/B0-08-044655-8/00141-0
关键词: Heteroatom 、 Organic chemistry 、 Medicinal chemistry 、 Substituent 、 Halogen 、 Isocyanide 、 Nucleophile 、 Chalcogen 、 Chlorine 、 Chemistry 、 Double bond
摘要: Recent methods for the preparation of compounds bearing a carbonnitrogen double bond and two heteroatom substituents on carbon are described. The chapter is restricted to with at least one halogen substituent (usually chlorine bromine) those chalcogen (oxygen, sulfur, or selenium). most important classes such carbonimidic dichlorides (also known as isocyanide dichlorides), isoureas, isothioureas, isoselenoureas. Carbonimidic available by variety methods, including addition isocyanides chlorination isothiocyanates. Several other in this can be obtained from nucleophilic displacement both atoms. Isothioureas isoselenoureas commonly alkylation thioureas selenoureas.