Medical device coating with a biocompatible layer

作者: Brandon M. Felkins , Victor W. Mccray , Paul Cook , Karen Havenstrite

DOI:

关键词: CoatingPolyethylene glycolChemical engineeringPolyacrylamideConjugateLayer (electronics)PEG ratioCovalent bondPolymerMaterials science

摘要: Medical devices with a hydrogel layer covalently attached to portion of the outer surface medical device are provided along methods for applying coating. The can include first polymer species comprising polyethylene glycol (PEG) and second species. Examples PEG polyacrylamide (PAM). be at least partially cross-linked. Methods forming coatings on including nucleophilic conjugate reactions, such as Click reactions.

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