Vaccine immunotherapy for treating hepatocellular cancer in immune suppressed patients
作者： John W. Hadden
DOI:
关键词: Immune system 、 Lymph node 、 Immunity 、 Cancer 、 Immunization 、 Immunology 、 Antigen 、 Immunotherapy 、 Medicine 、 Adjuvant
摘要: A method for overcoming mild to moderate immune suppression includes the steps of inducing production naive T-cells and restoring T-cell immunity. vaccine immunotherapy exposing endogenous or exogenous antigens at an appropriate site. Additionally, a unblocking immunization regional lymph node promoting differentiation maturation immature dendritic cells allowing presentation processed peptides by resulting mature cells, thus, example, tumor gain T-cells. Further, treating cancer other persistent lesions administering effective amount natural cytokine mixture as adjuvant administered antigen lesions.
lens.org 参考文章(251)
Ulrich Stollenwerk, Ilona Werner, Christian Birr, heir by Paul Stollenwerk, heir by Margot Stollenwerk, Medicaments containing alpha 1 thymosin fragments and having an immunostimulant action, and fragments of alpha 1 thymosin ,(1986)
Arie Belldegrun, Steven A. Rosenberg, Adoptive immunotherapy of urologic tumors. Cancer treatment and research. ,vol. 46, pp. 213- 233 ,(1989) , 10.1007/978-1-4613-1595-7_12
Derek N.J. Hart, Dendritic cells: unique leukocyte populations which control the primary immune response. Blood. ,vol. 90, pp. 3245- 3287 ,(1997) , 10.1182/BLOOD.V90.9.3245
C. J. M. Van Noesel, L. A. Aarden, M. Brouwer, R. A. W. Van Lier, V. I. Rebel, Immobilized anti-CD3 monoclonal antibodies induce accessory cell-independent lymphokine production, proliferation and helper activity in human T lymphocytes. Immunology. ,vol. 68, pp. 45- 50 ,(1989)
J L Ceuppens, F Van Vaeck, J Van Damme, J Verwilghen, M L Baroja, Differences in the stimulating capacity of immobilized anti-CD3 monoclonal antibodies: variable dependence on interleukin-1 as a helper signal for T-cell activation. Immunology. ,vol. 72, pp. 269- 276 ,(1991)
Romana Mikyšková, Jan Bubeník, Luis Mendoza, Vladimír Vonka, Michal Šmahel, Jana Šímová, Táňa Jandlová, Local cytokine treatment of HPV16-associated tumours results in inhibition of their lung metastases. Clinical & Experimental Metastasis. ,vol. 18, pp. 581- 587 ,(2000) , 10.1023/A:1011987206008
Allan L. Goldstein, Teresa L. K. Low, Su-Sun Wang, Chun-Yen Lai, Thymosin alpha 1 ,(1977)
Ulrich Stollenwerk, Ilona Werner, Christian Birr, Medicaments containing thymosin alpha 1 fragments and having an immunostimulant action, and fragments of thymosin alpha 1 ,(1980)
John W. Hadden, Immunology of Head and Neck Cancer Clinical Immunotherapeutics. ,vol. 3, pp. 362- 385 ,(1995) , 10.1007/BF03259502
John W. Hadden, Elba M. Hadden, Elliott Middleton, Lymphocyte blast transformation. I. Demonstration of adrenergic receptors in human peripheral lymphocytes. Cellular Immunology. ,vol. 1, pp. 583- 595 ,(1970) , 10.1016/0008-8749(70)90024-9