Bioengineered silk protein-based nucleic acid delivery systems
作者： David L. Kaplan , Keiji Numata
DOI:
关键词: Delivery system 、 Transfection 、 SILK 、 Recombinant DNA 、 Nucleic acid 、 Controlled release 、 Materials science 、 Biocompatibility 、 Biochemistry 、 Cell selectivity
摘要: Nucleic acid transfer is achieved using a silk-based delivery system which releases nucleic acids from complexes. The complexes, are composed, for example, of plasmid DNA (pDNA) and recombinant silk containing polycation specific polypeptides sequences, can show high biocompatibility, efficiency, cell selectivity controlled release transfection.
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