A Three-dimensional Polymer Scaffolding Material Exhibiting a Zero Poisson’s Ratio

摘要: Poisson's ratio describes the degree to which a material contracts (expands) transversally when axially strained. A with zero does not deform in response an axial strain (stretching). In tissue engineering applications, scaffolding having (ZPR) may be more suitable for emulating behavior of native tissues and accommodating transmitting forces host site during wound healing (or regrowth). For example, beneficial cartilage, ligament, corneal, brain tissues, are known possess ratios nearly zero. Here, we report 3D biomaterial constructed from polyethylene glycol (PEG) exhibiting in-plane large values strain. We use digital micro-mirror device projection printing (DMD-PP) create single- double-layer scaffolds composed semi-re-entrant pores whose arrangement deformation mechanisms contribute ratio. Strain experiments prove that addition layers change Human mesenchymal stem cells (hMSCs) cultured on biomaterials demonstrate feasibility utilizing these novel materials biological applications require little no transverse deformations resulting strains. Techniques used this work allow both scale-independent independent choice strut strains elastic regime, therefore ZPR can imparted variety photocurable biomaterials.