Clinical and Molecular Analysis of Patients with Renal Hypouricemia in Japan-Influence of URAT1 Gene on Urinary Urate Excretion
作者： Kimiyoshi Ichida , Makoto Hosoyamada , Ichiro Hisatome , Atsushi Enomoto , Miho Hikita
DOI: 10.1097/01.ASN.0000105320.04395.D0
关键词: Benzbromarone 、 Urate transport 、 Apical membrane 、 Hypouricemia 、 Uricosuric 、 Compound heterozygosity 、 SLC22A12 、 Renal function 、 Internal medicine 、 Endocrinology 、 Medicine
摘要: … (URAT1 encoded by SLC22A12), located at the apical membrane in the proximal tubules. We also demonstrated that URAT1 … and the significance of URAT1 in maintaining serum urate …
asnjournals.org参考文章(36)
Françoise Roch-Ramel, Barbara Guisan, Jacques Diezi, Effects of Uricosuric and Antiuricosuric Agents on Urate Transport in Human Brush-Border Membrane Vesicles Journal of Pharmacology and Experimental Therapeutics. ,vol. 280, pp. 839- 845 ,(1997)
Kimiyoshi Ichida, Makoto Hosoyamada, Hiroaki Kimura, Michio Takeda, Yasunori Utsunomiya, Tatsuo Hosoya, Hitoshi Endou, Urate transport via human PAH transporter hOAT1 and its gene structure Kidney International. ,vol. 63, pp. 143- 155 ,(2003) , 10.1046/J.1523-1755.2003.00710.X
Jane Y. Yeun, James A. Hasbargen, Renal hypouricemia: Prevention of exercise-induced acute renal failure and a review of the literature American Journal of Kidney Diseases. ,vol. 25, pp. 937- 946 ,(1995) , 10.1016/0272-6386(95)90579-0
Ichiro Hisatome, Kazuhide Ogino, Makoto Saito, Jiro Miyamoto, Junichi Hasegawa, Hiroshi Kotake, Hiroto Mashiba, Shoji Nakamoto, Renal Hypouricemia due to an Isolated Renal Defect of Urate Transport Nephron. ,vol. 49, pp. 81- 83 ,(1988) , 10.1159/000184991
K Ichida, Y Amaya, N Kamatani, T Nishino, T Hosoya, O Sakai, Identification of two mutations in human xanthine dehydrogenase gene responsible for classical type I xanthinuria. Journal of Clinical Investigation. ,vol. 99, pp. 2391- 2397 ,(1997) , 10.1172/JCI119421
M Ninomiya, Y Ito, A Nishi, T Matsumoto, A Kogal, Y Hori, H Nishida, G Nomura, H Kato, Recurrent exercise‐induced acute renal failure in renal hypouricemia Acta Paediatrica. ,vol. 85, pp. 1009- 1011 ,(1996) , 10.1111/J.1651-2227.1996.TB14206.X
Albert Y. Hung, Morgan Sheng, PDZ domains: structural modules for protein complex assembly. Journal of Biological Chemistry. ,vol. 277, pp. 5699- 5702 ,(2002) , 10.1074/JBC.R100065200
Ichiro Hisatome, Kazuhide Ogino, Hiroshi Kotake, Riichiro Ishiko, Makoto Saito, Junichi Hasegawa, Hiroto Mashiba, Shoji Nakamoto, Cause of persistent hypouricemia in outpatients. Nephron. ,vol. 51, pp. 13- 16 ,(1989) , 10.1159/000185233
L B Sorensen, D J Levinson, Isolated defect in postsecretory reabsorption of uric acid. Annals of the Rheumatic Diseases. ,vol. 39, pp. 180- 183 ,(1980) , 10.1136/ARD.39.2.180
Ch. M. M. Erley, R. R. Hirschberg, W. Hoefer, K. Schaefer, Acute renal failure due to uric acid nephropathy in a patient with renal hypouricemia Journal of Molecular Medicine. ,vol. 67, pp. 308- 312 ,(1989) , 10.1007/BF01892900