Andropause Clinical Implications of the Decline in Serum Testosterone Levels With Aging in Men

作者: A. M. Matsumoto

DOI: 10.1093/GERONA/57.2.M76

关键词: MedicineClinical significanceSerum testosteroneInternal medicineClinical syndromeSexual functionEndocrinologyPhysical functionAndrogen deficiencyandropauseHormone replacement therapy (female-to-male)

摘要: T is now well accepted that serum testosterone (T) levels decline progressively with aging in men (1‐5). This associated alterations body composition; diminished energy, muscle strength, and physical function; reduced sexual depressed mood; decreased cognitive function. Similar changes occur young androgen deficiency are improved replacement therapy. However, the physiological clinical significance of aging-associated unclear, particularly because may remain within normal range for men. From a practical standpoint, it most appropriate to define “andropause” as an age-related older below syndrome (i.e., symptoms signs) consistent deficiency. The consequence both per se age-associated comorbid illnesses medications used treat them

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