Monitoring the treatment and health of patients accessing HIV care in low and middle-income countries

作者: SJ Hoskins

DOI:

关键词: PediatricsDeveloping countryMedicineTanzaniaPopulationAntiretroviral therapyEnvironmental healthLow and middle income countriesConcordanceMeasure outcomesHuman immunodeficiency virus (HIV)

摘要: Monitoring patient health in low and middle-income country HIV care programmes is challenging, as, without evidence, measurement tools derived from high-income studies have been adapted paper-based monitoring systems quickly developed. An accurate understanding of the population may be compromised. This thesis examines aspects care: access to Cotrimoxazole preventive therapy (CPT), prevalence common mental disorders (CMD), used measure outcomes on antiretroviral (ART). CPT frequently cited as being 4% with few estimating long-term access. Estimated CMD varies widely little standardisation exists. And, while international ART programme recommendations exist, no study has compared concordance, or otherwise, between information collected different countries. The first this thesis, Ugandan Tanzanian patients, estimates time diagnosis initiation, spent associated factors. These are reported data. coverage were poor. absence unique identifiers means data cannot distinguish patients who diagnosed initiate reporting periods. Furthermore, officially reported. second factors among HIV-positive Ugandans, validates for this. Prevalence was around 10% but routinely-collected identified at-risk patients. Measurement tool validity poor, their use substantially overestimates prevalence. third compares Malawi, Uganda, Ukraine Tanzania. There concordance recommendations, discordance additional data-items paediatric age-groupings. signalled a lack how best monitor treated populations. Finally, fourth proposed aim assessing predictive value existing programmatic systems.

参考文章(256)
AD Harries, R Zachariah, MP Spielmann, E Bakali, P Gomani, Cotrimoxazole prophylaxis in HIV-infected individuals after completing anti-tuberculosis treatment in Thyolo, Malawi. International Journal of Tuberculosis and Lung Disease. ,vol. 6, pp. 1046- 1050 ,(2002)
G. Barungi, W. Nakahima, M. Jangano, E. Chidziva, M. Teopista, L. Chakonza, M. Nakazibwe, A. Mawora, G. Nassuna, C. Maweni, E. Chigwedere, M. Matongo, J. Komugyena, P. Khauka, P. Muygenyi, S. Chitsungo, A. Kambungu, T. Mupudzi, F. Sematala, H. Katabira, D. Masiira, C. Zawedde, C. Tumusiime, F. Mapinge, R. Warara, C. Muvirimi, N. Rutikarayo, T. Otim, K. Wangati, L. Generous, J. Chimanzi, R. Nairubi, E. Bulume, H. Chirairo, M. Namyalo, P. Ocitti, J. Sabiiti, A. Atwine, E. Katabira, D. Winogron, S. Murungi, A. Drasiku, C. Puddephatt, P. Mwesigwa, N. Mdege, G. Musoro, C. Twijukye, D. Yirrell, C. Kityo, F. Ssali, A. Muhwezi, N. Ngorima, B. Etukoit, R. Kasirye, H. Grosskurth, P. Kaleebu, P. Munderi, J. Machingura, S. Makota, C. Gilks, D. Nsibambi, M. Pascoe, C. Gale, G. Kabuye, D. Tumukunde, F. Lyagoba, R. Nalumenya, D. M. Gibb, M. Palmer, D. Bray, L. Vere, K. Taylor, A. Babiker, A. Coutinho, J. Oyugi, P. Naidoo, C. Hill, R. Massa, R. Enzama, J. Darbyshire, G. Mulindwa, A. Burke, S. Sheehan, A. Pozniak, A. McLaren, P. Hughes, C. V. Gale, A. Ronald, A. Reid, P. Mugyenyi, S. Bahendeka, D. Pillay, K. Boocock, K. Moyo, I. Machingura, J. Hakim, M. Phiri, M. Bassett, J. Leith, A. Latif, L. Mugarura, M. Aber, B. Amuron, J. M. Steens, F. Taziwa, R. Byaruhanga, E. Loeliger, H. Byakwaga, A. Zalwango, O. Mugurungi, J. Tukamushaba, A. Jamu, B. Gazzard, A. Mukose, A. S. Walker, S. Tugume, J. Nakiyingi-Miiro, D. Serwadda, J. Rooney, H. Kyomugisha, D. Atwine, H. Byomire, G. Tinago, M. Rauchenberger, L. Peto, J. Martin, J. Okiror, S. Mutsai, M. Ait-Khaled, A. Mugisha, T. Bakainyaga Grace, A. Chogo Wapakhabulo, L. Namale, I. Weller, J. Matenga, H. Wilkes, S. Mudzingwa, M. Chirara, E. Zalwango, B. Kikaire, J. H. Darbyshire, V. Robertson, Virological response to a triple nucleoside/nucleotide analogue regimen over 48 weeks in HIV-1-infected adults in Africa AIDS. ,vol. 20, pp. 1391- 1399 ,(2006)
A Douaihy, N Singh, Factors affecting quality of life in patients with HIV infection. Aids Reader. ,vol. 11, pp. 450- 475 ,(2001)
RB Chimzizi, AD Harries, FM Salaniponi, A Khonyongwa, E Manda, Counselling, HIV testing and adjunctive cotrimoxazole for TB patients in Malawi: from research to routine implementation. International Journal of Tuberculosis and Lung Disease. ,vol. 8, pp. 938- 944 ,(2004)
AD Harries, FM Salaniponi, R Zachariah, M Spielmann, P Gomani, Arendt, E Panarotto, R Wennig, S Schneider, Compliance with cotrimoxazole prophylaxis for the prevention of opportunistic infections in HIV-positive tuberculosis patients in Thyolo district, Malawi. International Journal of Tuberculosis and Lung Disease. ,vol. 5, pp. 843- 846 ,(2001)
Rosalyn E. Stahl, Alvin Friedman-Kien, Ronald Dubin, Michael Marmor, Susan Zolla-Pazner, Immunologic abnormalities in homosexual men: Relationship to Kaposi's sarcoma The American Journal of Medicine. ,vol. 73, pp. 171- 178 ,(1982) , 10.1016/0002-9343(82)90174-7
M. Etienne, L. Burrows, B. Osotimehin, T. Macharia, B. Hossain, R. R. Redfield, A. Amoroso, Situational analysis of varying models of adherence support and loss to follow up rates; findings from 27 treatment facilities in eight resource limited countries. Tropical Medicine & International Health. ,vol. 15, pp. 76- 81 ,(2010) , 10.1111/J.1365-3156.2010.02513.X
Paul E. Bebbington, Population surveys of psychiatric disorder and the need for treatment. Social Psychiatry and Psychiatric Epidemiology. ,vol. 25, pp. 33- 40 ,(1990) , 10.1007/BF00789068
G. Somi, S. C. Keogh, J. Todd, B. Kilama, A. Wringe, J. van den Hombergh, K. Malima, R. Josiah, M. Urassa, R. Swai, B. Zaba, Low mortality risk but high loss to follow-up among patients in the Tanzanian national HIV care and treatment programme. Tropical Medicine & International Health. ,vol. 17, pp. 497- 506 ,(2012) , 10.1111/J.1365-3156.2011.02952.X