Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases
作者： B. V. Sauter , O. Martinet , W.-J. Zhang , J. Mandeli , S. L. C. Woo
关键词: Adenoviridae 、 Cancer research 、 Angiogenesis 、 Genetic enhancement 、 Endostatin 、 Transgene 、 Endothelial stem cell 、 Lewis lung carcinoma 、 Biology 、 In vivo
摘要: … We have constructed a recombinant adenovirus that ex… administration of the vector to nude mice, which resulted in … 64 mm3), recombinant adenovirus was injected iv by tail vein (in nine …
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Thomas Boehm, Judah Folkman, Timothy Browder, Michael S. O'Reilly, Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance Nature. ,vol. 390, pp. 404- 407 ,(1997) , 10.1038/37126
William R. Black, R. Christopher Agner, Tumour regression after endostatin therapy Nature. ,vol. 391, pp. 450- 450 ,(1998) , 10.1038/35064
A. James Mixson, Dhruv Kumar, Sanford A. Stass, Qing-Rong Chen, Liposomes complexed to plasmids encoding angiostatin and endostatin inhibit breast cancer in nude mice. Cancer Research. ,vol. 59, pp. 3308- 3312 ,(1999)
Thomas Boehm, Steven Pirie-Shepherd, Loc-Ba Trinh, Joseph Shiloach, Judah Folkman, Disruption of the KEX1 gene in Pichia pastoris allows expression of full-length murine and human endostatin. Yeast. ,vol. 15, pp. 563- 572 ,(1999) , 10.1002/(SICI)1097-0061(199905)15:7<563::AID-YEA398>3.0.CO;2-R
Mohanraj Dhanabal, Ramani Ramchandran, Matthew J. F. Waterman, Hua Lu, Bertrand Knebelmann, Mark Segal, Vikas P. Sukhatme, Endostatin induces endothelial cell apoptosis. Journal of Biological Chemistry. ,vol. 274, pp. 11721- 11726 ,(1999) , 10.1074/JBC.274.17.11721
Zhen Chang, Aung Choon, Andreas Friedl, Endostatin binds to blood vessels in situ independent of heparan sulfate and does not compete for fibroblast growth factor-2 binding. American Journal of Pathology. ,vol. 155, pp. 71- 76 ,(1999) , 10.1016/S0002-9440(10)65101-2
Douglas Hanahan, Judah Folkman, Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis Cell. ,vol. 86, pp. 353- 364 ,(1996) , 10.1016/S0092-8674(00)80108-7
Neil R. Hackett, Avner Yayon, Ronald G. Crystal, Hwai-Loong Kong, Dalit Hecht, Wenru Song, Imre Kovesdi, Regional Suppression of Tumor Growth by In Vivo Transfer of a cDNA Encoding a Secreted Form of the Extracellular Domain of the flt-1 Vascular Endothelial Growth Factor Receptor Human Gene Therapy. ,vol. 9, pp. 823- 833 ,(1998) , 10.1089/HUM.1998.9.6-823
P. Lin, J. A. Buxton, A. Acheson, C. Radziejewski, P. C. Maisonpierre, G. D. Yancopoulos, K. M. Channon, L. P. Hale, M. W. Dewhirst, S. E. George, K. G. Peters, Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2 Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 8829- 8834 ,(1998) , 10.1073/PNAS.95.15.8829
Judah Folkman, Patricia A. D'Amore, Blood Vessel Formation: What Is Its Molecular Basis? Cell. ,vol. 87, pp. 1153- 1155 ,(1996) , 10.1016/S0092-8674(00)81810-3