Inadequate corpus luteum function after the induction of ovulation in anoestrous ewes by LH-RH or an LH-RH agonist

作者: A. S. McNeilly , M. Hunter , R. B. Land , H. M. Fraser

DOI: 10.1530/JRF.0.0630137

关键词: AgonistChemistryScottish BlackfaceEndocrinologyCorpus luteumLuteal phaseOvulation inductionBuserelinOvulationReceptorInternal medicine

摘要: Scottish Blackface ewes were given LH-RH (3 x 30 micrograms i.v., at 90 min intervals) or D-Ser-(But)6-des Gly10 LH-Rh ethylamide (LH-RH agonist) as a single injection (8 40 micrograms) during anoestrus. Ovulation judged by laparoscopy occurred in 8 of the 27 animals. Despite fact that agonist induced greater release LH and FSH different treatments had no effect on number ovulating within each treatment group there was apparent difference amounts gonadotrophins released between did not ovulate. All ovulations resulted formation CL associated with plasma progesterone concentrations less than 1 ng/ml (1--5 normal luteal phase). In comparison cycle lower weight reduced content ability to secrete vitro. However, binding hCG equivalent CL. These results suggest inadequate formed anoestrous after have developed synthesize spite presence receptors.

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