Dose response and stability of silicone-based deformable radiochromic dosimeters (FlexyDos3D) using spectrophotometer and flatbed scanner
作者： Yi Du , Ruoxi Wang , Haizhen Yue , Yibao Zhang , Hao Wu
DOI: 10.1016/J.RADPHYSCHEM.2019.108574
关键词: Silicone 、 Visible spectrum 、 Biomedical engineering 、 Absorption (electromagnetic radiation) 、 Irradiation 、 Linearity 、 Materials science 、 Scanner 、 Radiotherapy dosimetry 、 Dosimeter
摘要: Abstract This study investigated the dose response and stability of dose-rate independent silicone-based radiochromic dosimeters (FlexyDos3D), which exhibit substantial potential in fabricating deformable anthropomorphic phantoms for radiotherapy dosimetry. The induced optical absorption changes were using two readout modalities: a UV-VIS spectrophotometer flatbed scanner. spectral measurement visible wavelength 400 nm–700 nm showed principle peak at 626 nm, secondary 424 nm valley area with minimal between around 470 nm. Dose strong linearity 0 90.3 Gy. was determined by measuring absorptions various times. phenomena increase dosimeters' density background (creep-up effect) decrease irradiated dosimeters’ (fading identified, these effects can be well depicted proposed dual-component model. gradient integrity assessed profiles that formed sharp dose-falloff. time-dependent indicated diminished fast over time.
sci-hub.se 参考文章(24)
C Baldock, Y De Deene, S Doran, G Ibbott, A Jirasek, M Lepage, K B McAuley, M Oldham, L J Schreiner, Polymer gel dosimetry Physics in Medicine and Biology. ,vol. 55, ,(2010) , 10.1088/0031-9155/55/5/R01
Titania Juang, Shiva Das, John Adamovics, Ron Benning, Mark Oldham, On the Need for Comprehensive Validation of Deformable Image Registration, Investigated With a Novel 3-Dimensional Deformable Dosimeter International Journal of Radiation Oncology*Biology*Physics. ,vol. 87, pp. 414- 421 ,(2013) , 10.1016/J.IJROBP.2013.05.045
E M Høye, P S Skyt, E S Yates, L P Muren, J B B Petersen, P Balling, A new dosimeter formulation for deformable 3D dose verification Journal of Physics: Conference Series. ,vol. 573, pp. 012067- ,(2015) , 10.1088/1742-6596/573/1/012067
Y De Deene, P S Skyt, R Hil, J T Booth, FlexyDos3D: a deformable anthropomorphic 3D radiation dosimeter: radiation properties* Physics in Medicine and Biology. ,vol. 60, pp. 1543- 1563 ,(2015) , 10.1088/0031-9155/60/4/1543
U. J. Yeo, M. L. Taylor, L. Dunn, T. Kron, R. L. Smith, R. D. Franich, A novel methodology for 3D deformable dosimetry Medical Physics. ,vol. 39, pp. 2203- 2213 ,(2012) , 10.1118/1.3694107
Slobodan Devic, Radiochromic film dosimetry: Past, present, and future Physica Medica. ,vol. 27, pp. 122- 134 ,(2011) , 10.1016/J.EJMP.2010.10.001
C McErlean, E Bräuer-Krisch, J Adamovics, M O Leach, S J Doran, High resolution 3D dosimetry for microbeam radiation therapy using optical CT Journal of Physics: Conference Series. ,vol. 573, pp. 012032- ,(2015) , 10.1088/1742-6596/573/1/012032
S J Doran, A T Abdul Rahman, E Bräuer-Krisch, T Brochard, J Adamovics, Ultra-high resolution optical CT dosimetry for the visualisation of synchrotron microbeam therapy doses 7th International Conference on 3D Radiation Dosimetry, IC3DDose 2012. ,vol. 444, pp. 012074- ,(2013) , 10.1088/1742-6596/444/1/012074
R D Franich, J R Supple, B Lindsay, U J Yeo, P Lonski, R L Smith, M L Taylor, L Dunn, T Kron, Reproducibility assessment of dynamically deforming DEFGEL in a respiratory motion phantom Journal of Physics: Conference Series. ,vol. 573, pp. 012024- ,(2015) , 10.1088/1742-6596/573/1/012024
E M Høye, P Balling, E S Yates, L P Muren, J B B Petersen, P S Skyt, Eliminating the dose-rate effect in a radiochromic silicone-based 3D dosimeter. Physics in Medicine and Biology. ,vol. 60, pp. 5557- 5570 ,(2015) , 10.1088/0031-9155/60/14/5557