Computer prediction and synthesis of new azoles based on N-benzoyl-N'-(9,10-dioxo-9,10-dihydroanthracen-1-yl)thioureas

摘要: New thiazole and 1,2,4-triazole derivatives of 9,10-anthraquinone were obtained by the reaction N-benzoyl-N'-(9,10-dioxo-9,10-dihydroanthracene-1-yl)-thioureas with bromoacetone in presence triethylamine hydrazine hydrate chloroform, respectively. The PASS computer program was used to predict biological activity spectra determine most promising activities for experimental testing. Thus, it has been shown that synthesized compounds are a class creation substances wide range activity. DOI: http://dx.doi.org/10.5755/j01.ct.64.2.6018