Aneurysms Increase the Risk of Rebleeding After Stereotactic Radiosurgery for Hemorrhagic Arteriovenous Malformations

摘要: Background and Purpose—The purpose of this study was to define the risk rebleeding after stereotactic radiosurgery (SRS) for hemorrhagic arteriovenous malformations with or without associated intracranial aneurysms. Methods—Between 1987 2006, we performed Gamma Knife SRS on 996 patients brain malformations; 407 had sustained an malformation hemorrhage. Sixty-four (16%) underwent prior embolization 84 (21%) surgical resection. The median target volume 2.3 mL (range, 0.1–20.7 mL). margin dose 20 Gy 13.5–27 Gy). Results—The overall rate total obliteration defined by angiography MRI 56%, 77%, 80%, 82% at 3, 4, 5, 10 years, respectively. Before obliteration, 33 (8%) additional hemorrhage SRS. annual until 1.3%. presence a patent aneurysm significantly increased rehemorrhage risk...