[Brain sex: just beginning to pave the way].

作者: Durval Damiani , Daniel Damiani , Taísa M. Ribeiro , Nuvarte Setian

DOI: 10.1590/S0004-27302005000100006

关键词: Sexual dimorphismSexually dimorphic nucleusTestosterone (patch)Clinical PracticeInternal medicineAnimal studiesEndocrinologyPhysiologyAromataseMedicineSex assignment

摘要: It has become clear that a sexual brain dimorphism exists between males and females animal studies have shown specific circuits developing depending on the sex. Since first by Gorski, in rats, characterizing sexually dimorphic nucleus pre optic area (SDN-POA) it been accepted male sex imprint is done estradiol, locally converted from testosterone through action of local aromatase. The presence estradiol inhibits apoptosis cells SDN, making bigger Other CNS regions we need marker to allow us identify these structures and, eventually, apply this information clinical practice. In intersex patients, may be value know which patient is, since had many doubts choosing rearing patients. not uncommon inadequacies occurred some causing lot discomfort suffering for himself as well his family. progression knowledge field bring another tool deal with difficult cases assignment

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