Controlled integration of gold nanoparticles and organic fluorophores using synthetically modified MS2 viral capsids.

摘要: The placement of fluorophores in close proximity to metal nanoparticle surfaces is proposed enhance several photophysical properties the dyes, potentially leading improved quantum yields and decreased photobleaching. It difficult practice, however, establish maintain nanoscale distances that are required maximize these effects. type metal, size, shape nanoparticle, physical distance separating from organic dye, spectral fluorophore itself all influence yield lifetime. This results a complex behavior can lead either enhanced or quenched fluorescence different contexts. In this report, we describe well-defined system be used explore effects, while physically preventing contacting surfaces. basis spherical protein capsid bacteriophage MS2, which was house gold partic...