Brain abscess due to Nocardia caviae. Report of a fatal outcome associated with abnormal phagocyte function.

作者: Robert W. Bradsher , Thomas P. Monson , Russell W. Steele

DOI: 10.1093/AJCP/78.1.124

关键词: ImmunologyNeutrophileBrain abscessSulfamethoxazoleAntibioticsMinocyclinePhagocyteAgar dilutionNocardiaMedicine

摘要: Nocardia is an uncommon cause of human disease. We report a patient with fatal brain abscess who had abnormal phagocyte function as measured by neutrophile chemotaxis, adherence, phagocytic function, and chemiluminescence in vitro Rebuck skin window vivo. Antimicrobial agar dilution susceptibility suggested minocycline was more active than sulfamethoxazole.

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