Natural product extracts of plant and marine origin having antileukemia potential. The NCI experience.

摘要: While effective treatments exist for acute lymphocytic leukemia (ALL), particularly in the case of children, and chronic mylogenous (CML), more efficacious other forms disease are still needed. The National Cancer Institute has tested over 90,000 extracts terrestrial plants marine invertebrates its human cancer one-dose/60-cell-line prescreen, results organisms meeting criteria established activity against selected cell lines presented. Taxonomic data limited to family genus plants, phylum organisms, those groups exhibiting significant (so-called "hot" families genera) discussed. plant Myrsinaceae Sapindaceae have not been studied any extent appear merit special attention, although line selectivity is also noted families.