Potential applications of gut microbiota to control human physiology.

摘要: The microorganisms living in our gut have been a black box to us for long time. However, with the recent advances high throughput DNA sequencing technologies, it is now possible assess virtually all including non-culturable ones. With use of powerful bioinformatics tools deal multivariate analyses huge amounts data from metagenomics, metatranscriptomics, metabolomics, we start gain some important insights into these tiny inhabitants. Our knowledge increasing about who they are, extent, what do and how affect health. Gut microbiota broad spectrum effects on health, preventing serious diseases, improving immune system health stimulating brain centers responsible appetite food intake control. Further, may be verge being capable manipulating by diet control possibly improve Diets consisting different components that are fermentable substrates kinds microbes gut. Thus, can used favor growth selected Nowadays, taken account as separate organ human body their activities metabolites many physiological neurological effects. In this mini-review, discuss diversity microbiota, technologies them, factors microbial composition physiology, potential applications satiety via gut-brain axis.