Inflammatory bowel disease in the Asia-Pacific area: a comparison with developed countries and regional differences.

摘要: The Asia-Pacific region has been marked as an area with a low incidence of inflammatory bowel disease (IBD), although confusion always existed to whether this was result diagnostic awareness, high infective diarrhoea and its overlap or true incidence. As epidemiological studies from are being made available it is clear that the prevalence rates IBD in compared Europe North America. They however, increasing rapidly. There substantial variations various ethnic groups Asia. highest recorded India, Japan Middle East there exists genetic predisposition South Asians (Indians, Pakistanis Bangladeshis) ulcerative colitis (UC). It appears certain racial more prone than others develop IBD. For instance, Indians South-East Asia have higher Chinese Malays. While host predisposition, environmental factor(s) may be responsible for difference. clinical phenotypes complication Asian resemble those Caucasian population general, but some heterogeneity observed different regions no evidence north-south east-west divide region. suggest UC hence appropriate time launch well-designed so etiopathogenetic factors can identified. male predominance Crohn's population. NOD2/CARD15 gene not associated CD Japanese, Korean, Indian