Pregnancy-related complications in women with reflux nephropathy.

摘要: Three hundred and forty-five pregnancies in 137 women with reflux nephropathy have been studied. All took place after 1971. Overall foetal loss was 48 (14%) of which only 6 (2%) were therapeutic abortions. Maternal complications (urine infection, hypertension, proteinuria, oedema, deterioration renal function, hematuria or stones) occurred alone combination 39% pregnancies. Fifty-two plasma creatinine (P.Cr > 0.11 mmol/l) prior to conception. Foetal 12 weeks gestation (excluding abortions) 18% compared 8% the 104 where maternal P.Cr known be < = o.11 per/l at conception (p 0.05). also more common impaired function group 0.001). Comparison unilateral versus bilateral scarring revealed no significant difference but an increased incidence over 50% scar 0.01). The pre-eclampsia higher scars, 50 (24%) than scars 8 (7%) Persistent vesicoureteric not associated risk. Impaired is pregnancy. Bilateral during