Cytotoxicity of Nanoparticles

作者: Nastassja Lewinski , Vicki Colvin , Rebekah Drezek

DOI: 10.1002/SMLL.200700595

关键词: CytotoxicityIn vitro cytotoxicityNanoparticleMaterials scienceHuman exposureNanotoxicologyMultiple factorsCarbon chemistryPotential toxicityNanotechnology

摘要: Human exposure to nanoparticles is inevitable as become more widely used and, a result, nanotoxicology research now gaining attention. However, while the number of nanoparticle types and applications continues increase, studies characterize their effects after address potential toxicity are few in comparison. In medical field particular, being utilized diagnostic therapeutic tools better understand, detect, treat human diseases. Exposure for purposes involves intentional contact or administration; therefore, understanding properties effect on body crucial before clinical use can occur. This Review presents summary vitro cytotoxicity data currently available three classes nanoparticles. With each these nanoparticles, different has been published about due varying experimental conditions well differing physiochemical properties. For move into arena, it important that uncovers understands how multiple factors influence so undesirable be avoided.

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