Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors.
作者： Shuwen Liu , Gengfu Xiao , Yibang Chen , Yuxian He , Jinkui Niu
DOI: 10.1016/S0140-6736(04)15788-7
关键词: Heptad repeat 、 Circular dichroism 、 Polyacrylamide gel electrophoresis 、 Gp41 、 Peptide 、 Coronavirus 、 Biophysics 、 Glycoprotein 、 Biochemistry 、 Biology 、 Transmembrane protein
摘要: … the fusogenic mechanism mediated by SARS-CoV spike protein and the mechanism by which CP-1 inhibits SARS-CoV infection (figure 8). In the native state, spike proteins on the virus …
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