Kinetics of Ion Pumps and Channels

作者: Weijiu Liu

DOI: 10.1007/978-88-470-2490-8_6

关键词: CalciumSodium channelChemistrySodiumSTIM1Voltage-dependent calcium channelBiophysicsRespiratory chainSERCACytosol

摘要: Various ions, such as Ca2+, Na+, and K+, enter exit a cell through selective ion pumps channels, potassium voltage-gated sodium calcium sodium/calcium exchangers, plasma membrane (PM) ATPases, demonstrated in Fig. 6.1. Calcium ions Ca2+ the cytosol store-operated channels (SOC) (VGCC). The sarcoplasmic or endoplasmic reticulum Ca2+-ATPases (SERCA) pump from into (ER) ER are released to inositol (1,4,5)-trisphosphate (IP3)- Ca2+-mediated receptors (IP3R). mitochondrion uniporters Ca2+/Na+ antiporters. (PMCA) exchangers. Depletion of stores causes STIM1 move ER-PM junctions, bind Orai1, activate for entry [63]. Sodium Na+ (NC) N+/K+ ATPases (NKA). Potassium K+ ATP-sensitive (ATPKC), delayed rectifying (DrKC), calcium-activated (CAKC). H+ ejected by respiratory chain driven energy oxidation NADP, which produced tricarboxylic acid cycle (TAC, also called Krebs cycle).

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