pH- and thermo-responsive solution behavior of amphiphilic, linear triblock terpolymers
作者： Athanasios Skandalis , Stergios Pispas
DOI: 10.1016/J.POLYMER.2018.10.023
关键词: Micelle 、 Lower critical solution temperature 、 Polyelectrolyte 、 Ethyl acrylate 、 Chemistry 、 Amphiphile 、 Tertiary amine 、 Cationic polymerization 、 Chemical engineering 、 Reversible addition−fragmentation chain-transfer polymerization
摘要: Abstract We report on the synthesis and self-assembly in aqueous media, of novel amphiphilic double-responsive (temperature pH) linear triblock terpolymers having chain structure poly(n-butyl acrylate-b-N-isopropylacrylamide-b-2-(dimethylamino) ethyl acrylate) (PnBA-b-PNIPAM-PDMAEA). The were synthesized by sequential RAFT polymerization molecularly characterized SEC, 1H NMR FT-IR spectroscopy. tertiary amine groups PDMAEA block quaternized converted to strong cationic polyelectrolytes. Light scattering along with electron atomic force microscopy observations, revealed that PnBA-b-PNIPAM-b-PDMAEA form micelles PnBA cores mixed coronas solutions. present tendency for intermicellar aggregation, probably a result corona-corona interactions through hydrogen bonding. Increase temperature above LCST PNIPAM results further aggregation decrease overall size polymeric aggregates, due shrinking blocks. have been found spherical lower phenomena.
sci-hub.se 参考文章(62)
Angelo Azzi, The use of fluorescent probes for the study of membranes. Methods in Enzymology. ,vol. 32, pp. 234- 246 ,(1974) , 10.1016/0076-6879(74)32024-1
Bokyung Kim, Christopher N. Lam, Bradley D. Olsen, Nanopatterned Protein Films Directed by Ionic Complexation with Water-Soluble Diblock Copolymers Macromolecules. ,vol. 45, pp. 4572- 4580 ,(2012) , 10.1021/MA2024914
Hui Li, Wenwen Wang, Jiaojun Tan, Chunmei Li, Qiuyu Zhang, Synthesis and characterization of graft copolymers PnBA-g-PS by miniemulsion polymerization RSC Advances. ,vol. 5, pp. 45459- 45466 ,(2015) , 10.1039/C5RA06502J
Shin-ichi Yusa, Yoshihiko Shimada, Yoshiro Mitsukami, Tohei Yamamoto, Yotaro Morishima, pH-Responsive Micellization of Amphiphilic Diblock Copolymers Synthesized via Reversible Addition−Fragmentation Chain Transfer Polymerization Macromolecules. ,vol. 36, pp. 4208- 4215 ,(2003) , 10.1021/MA030065X
Kanjiro Miyata, Makoto Oba, Mitsunobu R. Kano, Shigeto Fukushima, Yelena Vachutinsky, Muri Han, Hiroyuki Koyama, Kohei Miyazono, Nobuhiro Nishiyama, Kazunori Kataoka, Polyplex Micelles from Triblock Copolymers Composed of Tandemly Aligned Segments with Biocompatible, Endosomal Escaping, and DNA-Condensing Functions for Systemic Gene Delivery to Pancreatic Tumor Tissue Pharmaceutical Research. ,vol. 25, pp. 2924- 2936 ,(2008) , 10.1007/S11095-008-9720-2
Douglas A. Davis, Andrew Hamilton, Jinglei Yang, Lee D. Cremar, Dara Van Gough, Stephanie L. Potisek, Mitchell T. Ong, Paul V. Braun, Todd J. Martínez, Scott R. White, Jeffrey S. Moore, Nancy R. Sottos, Force-induced activation of covalent bonds in mechanoresponsive polymeric materials Nature. ,vol. 459, pp. 68- 72 ,(2009) , 10.1038/NATURE07970
Murat Mertoglu, Sébastien Garnier, André Laschewsky, Katja Skrabania, Joachim Storsberg, Stimuli responsive amphiphilic block copolymers for aqueous media synthesised via reversible addition fragmentation chain transfer polymerisation (RAFT) Polymer. ,vol. 46, pp. 7726- 7740 ,(2005) , 10.1016/J.POLYMER.2005.03.101
Jennifer E. Laaser, Yaming Jiang, Dustin Sprouse, Theresa M. Reineke, Timothy P. Lodge, pH- and Ionic-Strength-Induced Contraction of Polybasic Micelles in Buffered Aqueous Solutions Macromolecules. ,vol. 48, pp. 2677- 2685 ,(2015) , 10.1021/ACS.MACROMOL.5B00360
Katja Skrabania, Hans v. Berlepsch, Christoph Böttcher, André Laschewsky, Synthesis of Ternary, Hydrophilic—Lipophilic—Fluorophilic Block Copolymers by Consecutive RAFT Polymerizations and Their Self-Assembly into Multicompartment Micelles Macromolecules. ,vol. 43, pp. 271- 281 ,(2010) , 10.1021/MA901913F
Natthaporn Suchao-in, Suwabun Chirachanchai, Sébastien Perrier, pH- and thermo-multi-responsive fluorescent micelles from block copolymers via reversible addition fragmentation chain transfer (RAFT) polymerization Polymer. ,vol. 50, pp. 4151- 4158 ,(2009) , 10.1016/J.POLYMER.2009.06.047