Renal energy metabolism and regulation of sodium reabsorption.

作者: Fredrik Kiil

DOI: 10.1038/KI.1977.23

关键词: Renal chloride reabsorptionInternal medicineRenal sodium reabsorptionReabsorptionRenal protein reabsorptionSodiumTubular fluidRenal physiologyEndocrinologyRenal functionChemistry

摘要: A relationship between glomerular filtration rate (GFR) and tubular reabsorption during acute changes in GFR has been recognized since adequate methods for estimation of became available [1]. Early micropuncture studies [2] have shown that the already applied first part proximal tubules. It is now well established not only water permeable tubules but also virtually impermeable thick ascending limb Henle's loop (the diluting segment) participate regulation sodium so more than 10 to 15% filtered load delivered distal convoluted cortex. simple hypothesis composition fluid, variations GFR, alter reabsorption. In this review, evidence, mainly from experiments on dogs, presented show bicarbonate concentration fluid regulates reduction (glomerulotubular balance). segment, seems depend concentration.

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