Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma
作者： Xiang Chen , Elizabeth Stewart , Anang A Shelat , Chunxu Qu , Armita Bahrami
DOI: 10.1016/J.CCR.2013.11.002
关键词: Mutation 、 Cancer research 、 Loss of heterozygosity 、 Embryonal rhabdomyosarcoma 、 Biology 、 Sarcoma 、 Somatic evolution in cancer 、 Copy-number variation 、 Cancer 、 Rhabdomyosarcoma 、 Immunology
摘要: … identified in our discovery cohort, we performed targeted resequencing of all exons for 139 of those genes … Approximately half of the tumors had no mutations in any of the 139 genes, so …
core.ac.uk
elsevier.com
sci-hub.se 参考文章(43)
Mie Tsuruga, Yong Dang, Yoshihito Shiono, Syuichi Oka, Yoshimitsu Yamazaki, Differential effects of vitamin E and three hydrophilic antioxidants on the actinomycin D-induced and colcemid-accelerated apoptosis in human leukemia CMK-7 cell line Molecular and Cellular Biochemistry. ,vol. 250, pp. 131- 137 ,(2003) , 10.1023/A:1024912806686
M. R. Stratton, C. Fisher, C. S. Cooper, B. A. Gusterson, Detection of Point Mutations in N-ras and K-ras Genes of Human Embryonal Rhabdomyosarcomas Using Oligonucleotide Probes and the Polymerase Chain Reaction Cancer Research. ,vol. 49, pp. 6324- 6327 ,(1989)
E H Soule, A B Hamoudi, H M Reiman, H Shimada, M Beltangady, H Maurer, W A Newton, Histopathology of childhood sarcomas, Intergroup Rhabdomyosarcoma Studies I and II: clinicopathologic correlation. Journal of Clinical Oncology. ,vol. 6, pp. 67- 75 ,(1988) , 10.1200/JCO.1988.6.1.67
Alberto S. Pappo, James R. Anderson, William M. Crist, Moody D. Wharam, Phillip P. Breitfeld, Douglas Hawkins, R. Beverly Raney, Richard B. Womer, David M. Parham, Steven J. Qualman, Holcombe E. Grier, Survival After Relapse in Children and Adolescents With Rhabdomyosarcoma: A Report From the Intergroup Rhabdomyosarcoma Study Group Journal of Clinical Oncology. ,vol. 17, pp. 3487- 3493 ,(1999) , 10.1200/JCO.1999.17.11.3487
William M. Crist, James R. Anderson, Jane L. Meza, Christopher Fryer, R. Beverly Raney, Frederick B. Ruymann, John Breneman, Stephen J. Qualman, Eugene Wiener, Moody Wharam, Thom Lobe, Bruce Webber, Harold M. Maurer, Sarah S. Donaldson, Intergroup Rhabdomyosarcoma Study-IV: Results for Patients With Nonmetastatic Disease Journal of Clinical Oncology. ,vol. 19, pp. 3091- 3102 ,(2001) , 10.1200/JCO.2001.19.12.3091
Simona Ognjanovic, Amy M. Linabery, Bridget Charbonneau, Julie A. Ross, Trends in childhood rhabdomyosarcoma incidence and survival in the United States, 1975-2005. Cancer. ,vol. 115, pp. 4218- 4226 ,(2009) , 10.1002/CNCR.24465
P. Nowell, The clonal evolution of tumor cell populations Science. ,vol. 194, pp. 23- 28 ,(1976) , 10.1126/SCIENCE.959840
Giles Robinson, Matthew Parker, Tanya A. Kranenburg, Charles Lu, Xiang Chen, Li Ding, Timothy N. Phoenix, Erin Hedlund, Lei Wei, Xiaoyan Zhu, Nader Chalhoub, Suzanne J. Baker, Robert Huether, Richard Kriwacki, Natasha Curley, Radhika Thiruvenkatam, Jianmin Wang, Gang Wu, Michael Rusch, Xin Hong, Jared Becksfort, Pankaj Gupta, Jing Ma, John Easton, Bhavin Vadodaria, Arzu Onar-Thomas, Tong Lin, Shaoyi Li, Stanley Pounds, Steven Paugh, David Zhao, Daisuke Kawauchi, Martine F. Roussel, David Finkelstein, David W. Ellison, Ching C. Lau, Eric Bouffet, Tim Hassall, Sridharan Gururangan, Richard Cohn, Robert S. Fulton, Lucinda L. Fulton, David J. Dooling, Kerri Ochoa, Amar Gajjar, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Jinghui Zhang, Richard J. Gilbertson, Novel mutations target distinct subgroups of medulloblastoma Nature. ,vol. 488, pp. 43- 48 ,(2012) , 10.1038/NATURE11213
M. Gymnopoulos, M.-A. Elsliger, P. K. Vogt, Rare cancer-specific mutations in PIK3CA show gain of function Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 5569- 5574 ,(2007) , 10.1073/PNAS.0701005104
Y. Hu, G. Wu, M. Rusch, L. Lukes, K. H. Buetow, J. Zhang, K. W. Hunter, Integrated cross-species transcriptional network analysis of metastatic susceptibility Proceedings of the National Academy of Sciences of the United States of America. ,vol. 109, pp. 3184- 3189 ,(2012) , 10.1073/PNAS.1117872109