Molecular tinkering of G protein‐coupled receptors: an evolutionary success
作者： Joel Bockaert , Jean Philippe Pin
关键词: G protein-coupled receptor 、 Cell biology 、 Transmembrane protein 、 Protein structure 、 Rhodopsin-like receptors 、 G protein 、 Biology 、 GTPase-activating protein 、 PDZ domain 、 Transmembrane domain
摘要: Among membrane-bound receptors, the G protein-coupled receptors (GPCRs) are certainly the most diverse. They have been very successful during evolution, being capable of …
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MARTIN RODBELL, The role of GTP-binding proteins in signal transduction: from the sublimely simple to the conceptually complex. Current Topics in Cellular Regulation. ,vol. 32, pp. 1- 47 ,(1992) , 10.1016/B978-0-12-152832-4.50003-3
E.K. Baker, N.J. Colley, C.S. Zuker, The cyclophilin homolog NinaA functions as a chaperone, forming a stable complex in vivo with its protein target rhodopsin. The EMBO Journal. ,vol. 13, pp. 4886- 4895 ,(1994) , 10.1002/J.1460-2075.1994.TB06816.X
J.M. Baldwin, The probable arrangement of the helices in G protein‐coupled receptors. The EMBO Journal. ,vol. 12, pp. 1693- 1703 ,(1993) , 10.1002/J.1460-2075.1993.TB05814.X
Randy A. Hall, Richard T. Premont, Chung-Wai Chow, Jeremy T. Blitzer, Julie A. Pitcher, Audrey Claing, Robert H. Stoffel, Larry S. Barak, Shirish Shenolikar, Edward J. Weinman, Sergio Grinstein, Robert J. Lefkowitz, The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange. Nature. ,vol. 392, pp. 626- 630 ,(1998) , 10.1038/33458
Philippe Vernier, Bruno Cardinaud, Olivier Valdenaire, Hervé Philippe, Jean-Didier Vincent, An evolutionary view of drug-receptor interaction: the bioamine receptor family Trends in Pharmacological Sciences. ,vol. 16, pp. 375- 381 ,(1995) , 10.1016/S0165-6147(00)89078-1
Vinzenz M. Unger, Paul A. Hargrave, Joyce M. Baldwin, Gebhard F. X. Schertler, Arrangement of rhodopsin transmembrane α-helices Nature. ,vol. 389, pp. 203- 206 ,(1997) , 10.1038/38316
Julia H. White, Alan Wise, Martin J. Main, Andrew Green, Neil J. Fraser, Graham H. Disney, Ashley A. Barnes, Piers Emson, Steven M. Foord, Fiona H. Marshall, Heterodimerization is required for the formation of a functional GABAB receptor Nature. ,vol. 396, pp. 679- 682 ,(1998) , 10.1038/25354
Jean-Philippe Pin, The two faces of glutamate Nature. ,vol. 394, pp. 19- 21 ,(1998) , 10.1038/27771
Klemens Kaupmann, Barbara Malitschek, Valerie Schuler, Jakob Heid, Wolfgang Froestl, Pascal Beck, Johannes Mosbacher, Serge Bischoff, Akos Kulik, Ryuichi Shigemoto, Andreas Karschin, Bernhard Bettler, GABAB-RECEPTOR SUBTYPES ASSEMBLE INTO FUNCTIONAL HETEROMERIC COMPLEXES Nature. ,vol. 396, pp. 683- 687 ,(1998) , 10.1038/25360
Jürgen Wess, G-protein-coupled receptors: molecular mechanisms involved in receptor activation and selectivity of G-protein recognition. The FASEB Journal. ,vol. 11, pp. 346- 354 ,(1997) , 10.1096/FASEBJ.11.5.9141501